Why does the pharmaceutical industry need to monitor TOC(Total organic carbon)?
1. Cleaning in the pharmaceutical industry needs to monitor TOC
In the pharmaceutical industry, contamination by product residues and detergents can be prevented by cleaning equipment. However, there will be trace residues on the surface of the equipment after cleaning. To verify the cleaning effect, the verification methods are different for different residues. TOC analysis is an important quality control measure to ensure water purity and equipment cleanliness, and it is also a general index of the presence of organic impurities after cleaning. By analyzing the TOC content, the cleanliness of the cleaning can be further judged.
2. Water for instruments in the pharmaceutical industry needs to detect TOC
The sensitivity of analytical instruments and experimental methods has been continuously improved, and organic pollutants in pure water and ultrapure water have become a concern. High levels of organic pollutants in water can cause the following problems:
Decreased detection sensitivity
Poor detection limit
Poor reproducibility
Elevated blank background
Produce diffusive or non-diffusive effects
Fouling of separation of purification media
Microbial propagation
INNOVA Total Organic Carbon Analyzer (Analy C1500) can quickly analyze the TOC content in pure water and ultrapure water, equipped with online and offline analysis modes, which can be switched according to needs, providing solutions for TOC detection of cleaning and water in the pharmaceutical industry.
Analy C1500 Analysis Principle
Total organic carbon (TOC) is the total carbon content of organic matter in water. Under the irradiation of 185nm UV light, the organic matter will be oxidized to CO2 and H2O. Then CO2 is dissolved in water and converted into HCO3 - and CO3 2-, resulting in a change of conductivity. The total organic carbon content is calculated by detecting the trend of conductivity change.
Oxidation Cell Features
UV oxidation direct conductivity detection without chemical reagent
Safe and pollution-free, no routine maintenance required
High-power 185nm UV lamp with sufficient irradiation to improve the oxidation efficiency
Quartz glass material with the best UV transmission
A small amount of sample can be fully oxidized in a short time to ensure analysis accuracy
Reliable high precision conductance electrode, ensure stable and accurate data analysis
Immersion temperature sensor provides rapid reaction
Real-time monitor of UV lamp with fault alarm
Intelligent Human-Computer Interaction
5" high-definition LCD touch screen
Two working modes: On-line or Off-line analysis mode
Auto start control of internal pipeline draining or cleaning
Various numbers of analysis can be set according to different purposes
Display operating status and alarm pop-ups
Real time on-line viewing of data, USB port for data download
Equipped with printer to print data
Operation record tracking function
Innova offers a large variety of lab equipment and has been committed to delivering the highest quality lab equipment to medical device companies and laboratories worldwide. To learn more, visit our website https://www.innovabiomed.com, or contact us via info@innobiomed.com.
