ULT Freezer has important applications in the field of cell therapy, mainly in the following aspects:
Cell Preservation
ULT Freezer, especially those capable of maintaining -86°C, are used in cell therapy for long-term preservation of cell samples. This application is useful for storing stem cells, lymphocytes, etc., to ensure the activity of these cells until they are needed for treatment.
Preservation of vaccines and biological products
In the medical field, ultra-low temperature refrigerators are critical for the preservation of vaccines and biological products. These products need to be stored at specific temperature conditions to maintain their activity and potency, and ULT Freezer provide such conditions.
Scientific Research Use
In life science research, ultra-low temperature refrigerators are used to preserve a variety of biological samples, such as proteins, enzymes, viruses, etc. These samples need to be kept at extremely low temperatures to maintain their structural and functional integrity during the experimental process.
-86℃ ULT Freezer is also closely related to the effect of tumor biotherapy, with the wide application of tumor biotherapy technology, more and more tumor patients through biotherapy technology towards recovery. Tumor biological therapy, is divided into three steps: cell collection, cell culture, cell infusion. The most central part of this is cell culture. The quantity, quality and activity of cell culture determine the overall effect of biotherapy. And in the cell culture link, low temperature freezing technology is the key. The freezing effect of 86℃ ULT Freezer directly affects the quantity, quality and activity of cell culture.
Tumor patients who are eligible for surgery can have their tumor tissues preserved at the time of surgery, sealed in sterile centrifuge tubes, and sent to the laboratory, where the laboratory staff will aseptically process the tissues before sending them to the -86℃ refrigerator for freezing and storage, which is used to prepare autologous tumor antigens, loaded with DC cells, which can be targeted to accurately remove the cancer cells in the patient's body with the best results. The whole process completely ensures the aseptic freezing of tumor tissues.
Some tumor patients need combined treatment of biological cell immunotherapy and radiotherapy, or may need to adjust the optimal time for transfusion due to various reasons. In this case, the cells that have been cultured can be put into the -86℃ refrigerator for freezing and storage by using the programmed cooling, and the slow freezing can avoid the cell damage due to the formation of ice crystals. Then resuscitate the cells at the right time according to the program of radiotherapy, and adopt the method of rapid thawing when resuscitating the cells, so as to ensure that the extracellular crystals will be melted in a very short period of time, and to avoid the damage caused by the intracellular recrystallization due to the penetration of water into the cells by the slow thawing.
As an important part of medical equipment, medical ultra-low temperature refrigerator plays a vital role in many fields such as drug storage and biological sample preservation. With the continuous progress of technology and increasing medical needs, medical ultra-low temperature refrigerator will face more challenges and development opportunities. In the future, medical ultra-low-temperature refrigerators will continue to develop toward more precise temperature control, intelligent management, efficient energy use, expanded application areas, enhanced safety, customization and personalization, the application of IoT and cloud technology, and energy conservation and environmental protection. These developments will provide better equipment and services for the medical field and promote the progress and innovation of medical technology.
