Manual cleaning of stainless steel fermentor is difficult, an on-line automatic CIP cleaning system can be equipped to solve this problem. The CIP station includes water tank and alkali tank with heating function. The CIP cleaning program can be freely set according to the process, generally in the order of water washing, alkali washing, and water washing. Purified water is recommended for cleaning. A spray ball is installed inside the tank for spray cleaning. 100% fully cover of the tank surface, without blind spots and residue.